Diabetes fuels periodontal lesions via GLUT1-driven macrophage inflammaging

• Main Authors: Qian Wang (Author), Lulingxiao Nie (Author), Pengfei Zhao (Author), Xinyi Zhou (Author), Yi Ding (Author), Qianming Chen (Author), Qi Wang (Author)
• Format: Book
• Published: Nature Publishing Group, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Hyperglycemia induces chronic low-grade inflammation (inflammaging), which is a newly identified contributor to diabetes-related tissue lesions, including the inflammatory bone loss in periodontitis. It is also a secondary senescent pattern mediated by an increased burden of senescent cells...