<i>CYP3A5*3</i> and <i>SLCO1B1</i> c.521T>C Polymorphisms Influence the Pharmacokinetics of Atorvastatin and 2-Hydroxy Atorvastatin

• Главные авторы: Jin-Woo Park (Автор), Jong-Min Kim (Автор), Hwa-Young Lee (Автор), Jihyeon Noh (Автор), Kyoung-Ah Kim (Автор), Ji-Young Park (Автор)
• Формат: ‌
• Опубликовано: MDPI AG, 2022-07-01T00:00:00Z.
• Предметы: article
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There is a large variability in individual responses to atorvastatin administration. This study assessed the pharmacogenetic effects of solute carrier organic anion transporter family member 1B1 (<i>SLCO1B1</i>, c.388A>G and c.521T>C) and cytochrome P450 3A5 (<i>CYP3A5</i&...