<i>CYP3A5*3</i> and <i>SLCO1B1</i> c.521T>C Polymorphisms Influence the Pharmacokinetics of Atorvastatin and 2-Hydroxy Atorvastatin

• 主要な著者: Jin-Woo Park (著者), Jong-Min Kim (著者), Hwa-Young Lee (著者), Jihyeon Noh (著者), Kyoung-Ah Kim (著者), Ji-Young Park (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2022-07-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

There is a large variability in individual responses to atorvastatin administration. This study assessed the pharmacogenetic effects of solute carrier organic anion transporter family member 1B1 (<i>SLCO1B1</i>, c.388A>G and c.521T>C) and cytochrome P450 3A5 (<i>CYP3A5</i&...