SIRT6 Suppresses NFATc4 Expression and Activation in Cardiomyocyte Hypertrophy

NFATc4, a member from the Nuclear Factor of Activated T cells (NFATs) transcription factor family, plays a pivotal role in the development of cardiac hypertrophy. NFATc4 is dephosphorylated by calcineurin and translocated from the cytoplasm to the nucleus to regulate the expression of hypertrophic g...

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Main Authors: Zhenzhen Li (Author), Xiaoying Zhang (Author), Zhen Guo (Author), Yao Zhong (Author), Panxia Wang (Author), Jingyan Li (Author), Zhuoming Li (Author), Peiqing Liu (Author)
Format: Book
Published: Frontiers Media S.A., 2019-01-01T00:00:00Z.
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3rd Floor Main Library

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