Spectrum of Clinical Manifestations in Children With WT1 Mutation: Case Series and Literature Review

• Autori principali: Patricia Arroyo-Parejo Drayer (Autore), Wacharee Seeherunvong (Autore), Chryso P. Katsoufis (Autore), Marissa J. DeFreitas (Autore), Tossaporn Seeherunvong (Autore), Jayanthi Chandar (Autore), Carolyn L. Abitbol (Autore)
• Natura: Libro
• Pubblicazione: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

BackgroundMutations of the Wilms tumor suppressor-1 gene (WT1) are associated with life-threatening glomerulopathy, disorders of sexual development, Wilm's tumor, and gonadal malignancies. Our objectives were to describe the clinical presentations, age of progression, and onset of complications...