RRx-001 Exerts Neuroprotection Against LPS-Induced Microglia Activation and Neuroinflammation Through Disturbing the TLR4 Pathway

• Hoofdauteurs: Jie Fang (Auteur), Jing She (Auteur), Fang Lin (Auteur), Jun-Chao Wu (Auteur), Rong Han (Auteur), Rui Sheng (Auteur), Guanghui Wang (Auteur), Zheng-Hong Qin (Auteur)
• Formaat: Boek
• Gepubliceerd in: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Neuroinflammation plays an important role in the pathogenesis of many central nervous system diseases. Here, we investigated the effect of an anti-cancer compound RRx-001 on neuroinflammation and its possible new applications. BV2 cells and primary microglia cells were used to evaluate the role of R...