RRx-001 Exerts Neuroprotection Against LPS-Induced Microglia Activation and Neuroinflammation Through Disturbing the TLR4 Pathway

• मुख्य लेखकों: Jie Fang (लेखक), Jing She (लेखक), Fang Lin (लेखक), Jun-Chao Wu (लेखक), Rong Han (लेखक), Rui Sheng (लेखक), Guanghui Wang (लेखक), Zheng-Hong Qin (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2022-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Neuroinflammation plays an important role in the pathogenesis of many central nervous system diseases. Here, we investigated the effect of an anti-cancer compound RRx-001 on neuroinflammation and its possible new applications. BV2 cells and primary microglia cells were used to evaluate the role of R...