Synergistic activation of AMPK by AdipoR1/2 agonist and inhibitor of EDPs-EBP interaction recover NAFLD through enhancing mitochondrial function in mice

• Hoofdauteurs: Nazi Song (Auteur), Hongjiao Xu (Auteur), Shuohan Wu (Auteur), Suijia Luo (Auteur), Jingyao Xu (Auteur), Qian Zhao (Auteur), Rui Wang (Auteur), Xianxing Jiang (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2023-02-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Nonalcoholic fatty liver disease (NAFLD), especially nonalcoholic steatohepatitis (NASH), is a common hepatic manifestation of metabolic syndrome. However, there are no effective therapy to treat this devastating disease. Accumulating evidence suggests that the generation of elastin-derived peptides...