Synergistic activation of AMPK by AdipoR1/2 agonist and inhibitor of EDPs-EBP interaction recover NAFLD through enhancing mitochondrial function in mice

• Autores principales: Nazi Song (Autor), Hongjiao Xu (Autor), Shuohan Wu (Autor), Suijia Luo (Autor), Jingyao Xu (Autor), Qian Zhao (Autor), Rui Wang (Autor), Xianxing Jiang (Autor)
• Formato: Libro
• Publicado: Elsevier, 2023-02-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Nonalcoholic fatty liver disease (NAFLD), especially nonalcoholic steatohepatitis (NASH), is a common hepatic manifestation of metabolic syndrome. However, there are no effective therapy to treat this devastating disease. Accumulating evidence suggests that the generation of elastin-derived peptides...