Different Pharmacokinetics of Tramadol, O-Demethyltramadol and N-Demethyltramadol in Postoperative Surgical Patients From Those Observed in Medical Patients

• প্রধান লেখক: Nenad Neskovic (লেখক), Dario Mandic (লেখক), Saska Marczi (লেখক), Sonja Skiljic (লেখক), Gordana Kristek (লেখক), Hrvoje Vinkovic (লেখক), Boris Mraovic (লেখক), Zeljko Debeljak (লেখক), Slavica Kvolik (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Background: Most studies examining tramadol metabolism have been carried out in non-surgical patients and with oral tramadol. The aim of this study was 1) to measure concentrations of tramadol, O-demethyltramadol (ODT), and N-demethyltramadol (NDT) in the surgical patients admitted to the intensive...