The Statin Target HMG-Coenzyme a Reductase (Hmgcr) Regulates Sleep Homeostasis in <i>Drosophila</i>

• Главные авторы: Ahmed M. Alsehli (Автор), Sifang Liao (Автор), Mohamed H. Al-Sabri (Автор), Lukas Vasionis (Автор), Archana Purohit (Автор), Neha Behare (Автор), Laura E. Clemensson (Автор), Michael J. Williams (Автор), Helgi B. Schiöth (Автор)
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• Опубликовано: MDPI AG, 2022-01-01T00:00:00Z.
• Предметы: article
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Statins, HMG Coenzyme A Reductase (HMGCR) inhibitors, are a first-line therapy, used to reduce hypercholesterolemia and the risk for cardiovascular events. While sleep disturbances are recognized as a side-effect of statin treatment, the impact of statins on sleep is under debate. Using Drosophila,...