Activation of the AMPK-SIRT1 pathway contributes to protective effects of Salvianolic acid A against lipotoxicity in hepatocytes and NAFLD in mice

• Egile Nagusiak: Songtao Li (Egilea), Qianyu Qian (Egilea), Na Ying (Egilea), Jianfei Lai (Egilea), Luyan Feng (Egilea), Sitong Zheng (Egilea), Fusheng Jiang (Egilea), Qing Song (Egilea), Hui Chai (Egilea), Xiaobing Dou (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2020-11-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Background: Salvianolic acid A (Sal A), a natural polyphenol compound extracted from Radix Salvia miltiorrhiza (known as Danshen in China), possesses a variety of potential pharmacological activities. The aim of this study is to determine mechanisms of hepatoprotective effects of Sal A against lipot...