Activation of the AMPK-SIRT1 pathway contributes to protective effects of Salvianolic acid A against lipotoxicity in hepatocytes and NAFLD in mice

• Main Authors: Songtao Li (Author), Qianyu Qian (Author), Na Ying (Author), Jianfei Lai (Author), Luyan Feng (Author), Sitong Zheng (Author), Fusheng Jiang (Author), Qing Song (Author), Hui Chai (Author), Xiaobing Dou (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Salvianolic acid A (Sal A), a natural polyphenol compound extracted from Radix Salvia miltiorrhiza (known as Danshen in China), possesses a variety of potential pharmacological activities. The aim of this study is to determine mechanisms of hepatoprotective effects of Sal A against lipot...