Activation of the AMPK-SIRT1 pathway contributes to protective effects of Salvianolic acid A against lipotoxicity in hepatocytes and NAFLD in mice

• मुख्य लेखकों: Songtao Li (लेखक), Qianyu Qian (लेखक), Na Ying (लेखक), Jianfei Lai (लेखक), Luyan Feng (लेखक), Sitong Zheng (लेखक), Fusheng Jiang (लेखक), Qing Song (लेखक), Hui Chai (लेखक), Xiaobing Dou (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2020-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background: Salvianolic acid A (Sal A), a natural polyphenol compound extracted from Radix Salvia miltiorrhiza (known as Danshen in China), possesses a variety of potential pharmacological activities. The aim of this study is to determine mechanisms of hepatoprotective effects of Sal A against lipot...