Polymorphisms of methylenetetrahydrofolate reductase (MTHFR) and susceptibility to pediatric acute lymphoblastic leukemia in a German study population

• Asıl Yazarlar: Elsner Holger A (Yazar), Schlegelberger Brigitte (Yazar), Seidemann Kathrin (Yazar), Rehe Klaus (Yazar), Cario Gunnar (Yazar), Mehles Andrea (Yazar), Schnakenberg Eckart (Yazar), Welte Karl H (Yazar), Schrappe Martin (Yazar), Stanulla Martin (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2005-05-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Methylenetetrahydrofolate reductase (MTHFR) has a major impact on the regulation of the folic acid pathway due to conversion of 5,10-methylenetetrahydrofolate (methylene-THF) to 5-methyl-THF. Two common polymorphisms (677C>T and 1...