Oligonucleotide Delivery across the Caco-2 Monolayer: The Design and Evaluation of Self-Emulsifying Drug Delivery Systems (SEDDS)

• Asıl Yazarlar: Jana Kubackova (Yazar), Ondrej Holas (Yazar), Jarmila Zbytovska (Yazar), Barbora Vranikova (Yazar), Guanghong Zeng (Yazar), Petr Pavek (Yazar), Anette Mullertz (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: MDPI AG, 2021-03-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Oligonucleotides (OND) represent a promising therapeutic approach. However, their instability and low intestinal permeability hamper oral bioavailability. Well-established for oral delivery, self-emulsifying drug delivery systems (SEDDS) can overcome the weakness of other delivery systems such as lo...