Recurrent secondary genomic alterations in desmoplastic small round cell tumors

• Главные авторы: Warren A. Chow (Автор), Jiing-Kuan Yee (Автор), Walter Tsark (Автор), Xiwei Wu (Автор), Hanjun Qin (Автор), Min Guan (Автор), Jeffrey S. Ross (Автор), Siraj M. Ali (Автор), Sherri Z. Millis (Автор)
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• Опубликовано: BMC, 2020-05-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Abstract Background Desmoplastic small round cell tumor (DSRCT) is a rare, highly aggressive, translocation-associated soft-tissue sarcoma that primarily affects children, adolescents, and young adults, with a striking male predominance. It is characterized by t(11;22) generating a novel EWSR1-WT1 f...