Recurrent secondary genomic alterations in desmoplastic small round cell tumors

• Main Authors: Warren A. Chow (Author), Jiing-Kuan Yee (Author), Walter Tsark (Author), Xiwei Wu (Author), Hanjun Qin (Author), Min Guan (Author), Jeffrey S. Ross (Author), Siraj M. Ali (Author), Sherri Z. Millis (Author)
• Format: Book
• Published: BMC, 2020-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Desmoplastic small round cell tumor (DSRCT) is a rare, highly aggressive, translocation-associated soft-tissue sarcoma that primarily affects children, adolescents, and young adults, with a striking male predominance. It is characterized by t(11;22) generating a novel EWSR1-WT1 f...