Presence of GABAB Receptors Forming Heterodimers With GABAB1 and GABAB2 Subunits in Human Lower Esophageal Sphincter

Presence of GABAB Receptors Forming Heterodimers With GABAB1 and GABAB2 Subunits in Human Lower Esophageal Sphincter

Baclofen, a GABAB-receptor (GABABR) agonist has been proposed to be useful as therapeutic agent for the management of gastro-esophageal reflux disease, but whether the compound acts directly at the lower esophageal sphincter (LES) remains to be elucidated. We performed the present study to assess th...

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Main Authors: Yasuhiro Torashima (Author), Yasuhito Uezono (Author), Masato Kanaide (Author), Yuko Ando (Author), Akihito Enjoji (Author), Takashi Kanematsu (Author), Kohtaro Taniyama (Author)
Format: Book
Published: Elsevier, 2009-01-01T00:00:00Z.
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