Insulin gene polymorphisms in type 1 diabetes, Addison's disease and the polyglandular autoimmune syndrome type II

• Glavni autori: Hahner Stefanie (Autor), Reisch Nicole (Autor), Penna-Martinez Marissa (Autor), Meyer Gesine (Autor), Willenberg Holger S (Autor), Kahles Heinrich (Autor), Lange Britta (Autor), Ramos-Lopez Elizabeth (Autor), Seissler Jürgen (Autor), Badenhoop Klaus (Autor)
• Format: Knjiga
• Izdano: BMC, 2008-07-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Polymorphisms within the insulin gene can influence insulin expression in the pancreas and especially in the thymus, where self-antigens are processed, shaping the T cell repertoire into selftolerance, a process that protects from β-...