Development and validation of an ultra-performance liquid chromatography mass spectrometry/mass spectrometry method for simultaneous quantification of total and free mycophenolic acid and its metabolites in human plasma

• Main Authors: Napatsanan Tanathitiphuwarat (Author), Pannee Tanudechpong (Author), Pajaree Chariyavilaskul (Author), Nantaporn Prompila (Author), Nat Tansrisawad (Author), Apinya Tubtimrattana (Author), Supeecha Wittayalertpanya (Author)
• Format: Book
• Published: Wolters Kluwer Medknow Publications, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A reliable method has been validated using ultra-performance liquid chromatography mass spectrometry (MS)/MS for simultaneous evaluation of human plasma concentration of mycophenolic acid (MPA) and its major metabolites both total and free form. All analytes were extracted from plasma by simple prot...