Development and validation of an ultra-performance liquid chromatography mass spectrometry/mass spectrometry method for simultaneous quantification of total and free mycophenolic acid and its metabolites in human plasma

• Hlavní autoři: Napatsanan Tanathitiphuwarat (Autor), Pannee Tanudechpong (Autor), Pajaree Chariyavilaskul (Autor), Nantaporn Prompila (Autor), Nat Tansrisawad (Autor), Apinya Tubtimrattana (Autor), Supeecha Wittayalertpanya (Autor)
• Médium: Kniha
• Vydáno: Wolters Kluwer Medknow Publications, 2020-01-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

A reliable method has been validated using ultra-performance liquid chromatography mass spectrometry (MS)/MS for simultaneous evaluation of human plasma concentration of mycophenolic acid (MPA) and its major metabolites both total and free form. All analytes were extracted from plasma by simple prot...