Structural and Kinetic Characterization of Thymidine Kinase from Leishmania major.

Structural and Kinetic Characterization of Thymidine Kinase from Leishmania major.

Leishmania spp. is a protozoan parasite and the causative agent of leishmaniasis. Thymidine kinase (TK) catalyses the transfer of the γ-phosphate of ATP to 2'-deoxythymidine (dThd) forming thymidine monophosphate (dTMP). L. major Type II TK (LmTK) has been previously shown to be important for i...

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Main Authors: Jennifer Timm (Author), Cristina Bosch-Navarrete (Author), Eliseo Recio (Author), Joanne E Nettleship (Author), Heather Rada (Author), Dolores González-Pacanowska (Author), Keith S Wilson (Author)
Format: Book
Published: Public Library of Science (PLoS), 2015-05-01T00:00:00Z.
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3rd Floor Main Library

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