Recent developments of topoisomerase inhibitors: Clinical trials, emerging indications, novel molecules and global sales

Recent developments of topoisomerase inhibitors: Clinical trials, emerging indications, novel molecules and global sales

The nucleic acid topoisomerases (TOP) are an evolutionary conserved mechanism to solve topological problems within DNA and RNA that have been historically well-established as a chemotherapeutic target. During investigation of trends within clinical trials, we have identified a very high number of cl...

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Main Authors: Andrey D. Bondarev (Author), Jörgen Jonsson (Author), Vladimir N. Chubarev (Author), Vadim V. Tarasov (Author), Francisco Alejandro Lagunas-Rangel (Author), Helgi B. Schiöth (Author)
Format: Book
Published: Elsevier, 2024-11-01T00:00:00Z.
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3rd Floor Main Library

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