Kinome profiling of cholangiocarcinoma organoids reveals potential druggable targets that hold promise for treatment stratification

• Asıl Yazarlar: Ruby Lieshout (Yazar), Alessandra V. S. Faria (Yazar), Maikel P. Peppelenbosch (Yazar), Luc J. W. van der Laan (Yazar), Monique M. A. Verstegen (Yazar), Gwenny M. Fuhler (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: BMC, 2022-06-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract Background Cholangiocarcinoma is a rare but lethal cancer of the biliary tract. Its first-line treatment is currently restricted to chemotherapy, which provides limited clinical benefit. Kinase inhibitors targeting oncogenic intracellular signaling have changed the treatment paradigm of can...