Rapid CD4 decline prior to antiretroviral therapy predicts subsequent failure to reconstitute despite HIV viral suppression

• المؤلفون الرئيسيون: Majid Darraj (مؤلف), Leigh A. Shafer (مؤلف), Shanna Chan (مؤلف), Ken Kasper (مؤلف), Yoav Keynan (مؤلف)
• التنسيق: كتاب
• منشور في: Elsevier, 2018-03-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

HIV-1 infection is characterized by loss of CD4 T cells, leading to immunodeficiency. Initiation of antiretroviral therapy (ART) results in suppression of the viral load and increased CD4 counts. Both viral and host factors determine CD4 cell responses to ART with approximately 15-30% of individuals...