Rapid CD4 decline prior to antiretroviral therapy predicts subsequent failure to reconstitute despite HIV viral suppression

• Main Authors: Majid Darraj (Author), Leigh A. Shafer (Author), Shanna Chan (Author), Ken Kasper (Author), Yoav Keynan (Author)
• 格式: 圖書
• 出版: Elsevier, 2018-03-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

HIV-1 infection is characterized by loss of CD4 T cells, leading to immunodeficiency. Initiation of antiretroviral therapy (ART) results in suppression of the viral load and increased CD4 counts. Both viral and host factors determine CD4 cell responses to ART with approximately 15-30% of individuals...