Current Status of Oligonucleotide-Based Protein Degraders

Transcription factors (TFs) and RNA-binding proteins (RBPs) have long been considered undruggable, mainly because they lack ligand-binding sites and are equipped with flat and narrow protein surfaces. Protein-specific oligonucleotides have been harnessed to target these proteins with some satisfacto...

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Main Authors: Po-Chang Shih (Author), Miyako Naganuma (Author), Yosuke Demizu (Author), Mikihiko Naito (Author)
Format: Book
Published: MDPI AG, 2023-02-01T00:00:00Z.
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3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available