Tracing CLL-biased stereotyped immunoglobulin gene rearrangements in normal B cell subsets using a high-throughput immunogenetic approach

• Главные авторы: Monica Colombo (Автор), Davide Bagnara (Автор), Daniele Reverberi (Автор), Serena Matis (Автор), Martina Cardillo (Автор), Rosanna Massara (Автор), Luca Mastracci (Автор), Jean Louis Ravetti (Автор), Luca Agnelli (Автор), Antonino Neri (Автор), Michela Mazzocco (Автор), Margherita Squillario (Автор), Andrea Nicola Mazzarello (Автор), Giovanna Cutrona (Автор), Andreas Agathangelidis (Автор), Kostas Stamatopoulos (Автор), Manlio Ferrarini (Автор), Franco Fais (Автор)
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• Опубликовано: BMC, 2020-03-01T00:00:00Z.
• Предметы: article
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Abstract Background B cell receptor Immunoglobulin (BcR IG) repertoire of Chronic Lymphocytic Leukemia (CLL) is characterized by the expression of quasi-identical BcR IG. These are observed in approximately 30% of patients, defined as stereotyped receptors and subdivided into subsets based on specif...