Tracing CLL-biased stereotyped immunoglobulin gene rearrangements in normal B cell subsets using a high-throughput immunogenetic approach

• मुख्य लेखकों: Monica Colombo (लेखक), Davide Bagnara (लेखक), Daniele Reverberi (लेखक), Serena Matis (लेखक), Martina Cardillo (लेखक), Rosanna Massara (लेखक), Luca Mastracci (लेखक), Jean Louis Ravetti (लेखक), Luca Agnelli (लेखक), Antonino Neri (लेखक), Michela Mazzocco (लेखक), Margherita Squillario (लेखक), Andrea Nicola Mazzarello (लेखक), Giovanna Cutrona (लेखक), Andreas Agathangelidis (लेखक), Kostas Stamatopoulos (लेखक), Manlio Ferrarini (लेखक), Franco Fais (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2020-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background B cell receptor Immunoglobulin (BcR IG) repertoire of Chronic Lymphocytic Leukemia (CLL) is characterized by the expression of quasi-identical BcR IG. These are observed in approximately 30% of patients, defined as stereotyped receptors and subdivided into subsets based on specif...