Absolute bioavailability of a substance with cardioprotective activity (ALM-802) in rats

• Váldodahkkit: G. B. Kolyvanov (Dahkki), P. O. Bochkov (Dahkki), A. A. Litvin (Dahkki), R. V. Shevchenko (Dahkki), A. L. Podolko (Dahkki), V. P. Zherdev (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: LLC "Publisher OKI", 2022-01-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The pharmacokinetics of a new potential cardioprotective agent ALM-802 was studied in rats after single intravenous and intragastric administration at doses of 10 and 100 mg/kg, respectively. The absolute bioavailability was 4.45 %, which indicates the potential for the development of a dosage form...