Absolute bioavailability of a substance with cardioprotective activity (ALM-802) in rats

• Main Authors: G. B. Kolyvanov (Author), P. O. Bochkov (Author), A. A. Litvin (Author), R. V. Shevchenko (Author), A. L. Podolko (Author), V. P. Zherdev (Author)
• Format: Book
• Published: LLC "Publisher OKI", 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The pharmacokinetics of a new potential cardioprotective agent ALM-802 was studied in rats after single intravenous and intragastric administration at doses of 10 and 100 mg/kg, respectively. The absolute bioavailability was 4.45 %, which indicates the potential for the development of a dosage form...