Novel Types of Small RNA Exhibit Sequence- and Target-dependent Angiogenesis Suppression Without Activation of Toll-like Receptor 3 in an Age-related Macular Degeneration (AMD) Mouse Model

• Główni autorzy: Masakatsu Takanashi (Autor), Katsuko Sudo (Autor), Shinobu Ueda (Autor), Shin-Ichiro Ohno (Autor), Yuko Yamada (Autor), Yasuhiro Osakabe (Autor), Hiroshi Goto (Autor), Yoshimichi Matsunaga (Autor), Akio Ishikawa (Autor), Yoshihiko Usui (Autor), Masahiko Kuroda (Autor)
• Format: Książka
• Wydane: Elsevier, 2015-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

RNA interference (RNAi) has become a powerful tool for suppressing gene expression in vitro and in vivo. A great deal of evidence has demonstrated the potential for the use of synthetic small interfering RNAs (siRNAs) as therapeutic agents. However, the application of siRNA to clinical medicine is s...