Design and synthesis of new 3-((7-chloroquinolin-4-yl)amino)thiazolidin-4-one analogs as Mycobacterium tuberculosis DNA gyrase inhibitors

• Main Authors: Preeti S. Salve (Author), Prajakta Parchure (Author), Lisel Araujo (Author), Rohini S. Kavalapure (Author), Sunil S. Jalalpure (Author), Dharmarajan Sriram (Author), Vagolu Siva Krishna (Author), Madhu Rekha Estharla (Author), Shankar G. Alegaon (Author)
• Format: Book
• Published: SpringerOpen, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Tuberculosis is evidently a major health threat among human populations worldwide. The current study presents the synthesis of new 3-((7-chloroquinolin-4-yl)amino)thiazolidin-4-one analogs (4a-o) as potential Mycobacterium tuberculosis DNA gyrase inhibitors. DNA gyrase regulates...