Design and synthesis of new 3-((7-chloroquinolin-4-yl)amino)thiazolidin-4-one analogs as Mycobacterium tuberculosis DNA gyrase inhibitors

• Hauptverfasser: Preeti S. Salve (Verfasst von), Prajakta Parchure (Verfasst von), Lisel Araujo (Verfasst von), Rohini S. Kavalapure (Verfasst von), Sunil S. Jalalpure (Verfasst von), Dharmarajan Sriram (Verfasst von), Vagolu Siva Krishna (Verfasst von), Madhu Rekha Estharla (Verfasst von), Shankar G. Alegaon (Verfasst von)
• Format: Buch
• Veröffentlicht: SpringerOpen, 2021-01-01T00:00:00Z.
• Schlagworte: article
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Abstract Background Tuberculosis is evidently a major health threat among human populations worldwide. The current study presents the synthesis of new 3-((7-chloroquinolin-4-yl)amino)thiazolidin-4-one analogs (4a-o) as potential Mycobacterium tuberculosis DNA gyrase inhibitors. DNA gyrase regulates...