NPAS2 Contributes to Liver Fibrosis by Direct Transcriptional Activation of Hes1 in Hepatic Stellate Cells

• Главные авторы: Tao Yang (Автор), Peng Yuan (Автор), Yi Yang (Автор), Ning Liang (Автор), Qian Wang (Автор), Jing Li (Автор), Rui Lu (Автор), Hongxin Zhang (Автор), Jiao Mu (Автор), Zhaoyong Yan (Автор), Hulin Chang (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2019-12-01T00:00:00Z.
• Предметы: article
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Recently, emerging evidence shows that dysregulation of circadian genes is closely associated with liver fibrosis. However, how dysregulation of circadian genes promotes liver fibrosis is unknown. In this study, we show that neuronal PAS domain protein 2 (NPAS2), one of the core circadian molecules...