A Pharmacological Investigation of Eph-Ephrin Antagonism in Prostate Cancer: UniPR1331 Efficacy Evidence

• Auteurs principaux: Claudio Festuccia (Auteur), Miriam Corrado (Auteur), Alessandra Rossetti (Auteur), Riccardo Castelli (Auteur), Alessio Lodola (Auteur), Giovanni Luca Gravina (Auteur), Massimiliano Tognolini (Auteur), Carmine Giorgio (Auteur)
• Format: Livre
• Publié: MDPI AG, 2023-10-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

The Eph kinases are the largest receptor tyrosine kinases (RTKs) family in humans. PC3 human prostate adenocarcinoma cells are a well-established model for studying Eph-ephrin pharmacology as they naturally express a high level of EphA2, a promising target for new cancer therapies. A pharmacological...