A Pharmacological Investigation of Eph-Ephrin Antagonism in Prostate Cancer: UniPR1331 Efficacy Evidence

• मुख्य लेखकों: Claudio Festuccia (लेखक), Miriam Corrado (लेखक), Alessandra Rossetti (लेखक), Riccardo Castelli (लेखक), Alessio Lodola (लेखक), Giovanni Luca Gravina (लेखक), Massimiliano Tognolini (लेखक), Carmine Giorgio (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2023-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The Eph kinases are the largest receptor tyrosine kinases (RTKs) family in humans. PC3 human prostate adenocarcinoma cells are a well-established model for studying Eph-ephrin pharmacology as they naturally express a high level of EphA2, a promising target for new cancer therapies. A pharmacological...