A Pharmacological Investigation of Eph-Ephrin Antagonism in Prostate Cancer: UniPR1331 Efficacy Evidence

• Autors principals: Claudio Festuccia (Autor), Miriam Corrado (Autor), Alessandra Rossetti (Autor), Riccardo Castelli (Autor), Alessio Lodola (Autor), Giovanni Luca Gravina (Autor), Massimiliano Tognolini (Autor), Carmine Giorgio (Autor)
• Format: Llibre
• Publicat: MDPI AG, 2023-10-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

The Eph kinases are the largest receptor tyrosine kinases (RTKs) family in humans. PC3 human prostate adenocarcinoma cells are a well-established model for studying Eph-ephrin pharmacology as they naturally express a high level of EphA2, a promising target for new cancer therapies. A pharmacological...