CAR-T cell potency: from structural elements to vector backbone components

Abstract Chimeric antigen receptor (CAR) T cell therapy, in which a patient's own T lymphocytes are engineered to recognize and kill cancer cells, has achieved remarkable success in some hematological malignancies in preclinical and clinical trials, resulting in six FDA-approved CAR-T products...

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Hoofdauteurs: Marzieh Mazinani (Auteur), Fatemeh Rahbarizadeh (Auteur)
Formaat: Boek
Gepubliceerd in: BMC, 2022-09-01T00:00:00Z.
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