Inhibitory Effects of Antiparkinsonian Drugs and Caspase Inhibitors in a Parkinsonian Flatworm Model

• Hoofdauteurs: Yoshihisa Kitamura (Auteur), Masatoshi Inden (Auteur), Hisakazu Sanada (Auteur), Kazuyuki Takata (Auteur), Takashi Taniguchi (Auteur), Shun Shimohama (Auteur), Hidehumi Orii (Auteur), Makoto Mochii (Auteur), Kiyokazu Agata (Auteur), Kenji Watanabe (Auteur)
• Formaat: Boek
• Gepubliceerd in: Elsevier, 2003-01-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

It has been known that rotenone and 1-methyl-4-phenylpyridinium ion (MPP+, a metabolite of MPTP), which inhibit mitochondrial complex I, are useful tools for parkinsonian models in vertebrates such as primates and rodents. Planarian, an invertebrate flatworm, has a high potential for regeneration, a...