LINE-1 methylation is inherited in familial testicular cancer kindreds

• Main Authors: Gadalla Shahinaz M (Author), Korde Larissa (Author), Savage Sharon A (Author), Mirabello Lisa (Author), Greene Mark H (Author)
• Format: Book
• Published: BMC, 2010-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Testicular germ cell tumors (TGCT) are the most frequent cancers among young men. There is a clear familial component to TGCT etiology, but no high-penetrance susceptibility gene has been identified. Epigenetic aberrations of the gen...