In Silico Studies on GCP-Lys-OMe as a Potential 14-3-3σ Homodimer Stabilizer

14-3-3 sigma is a vital negative cell cycle regulator. Its expression is consistently downregulated in many types of cancer through gene promoter hypermethylation or proteasomal degradation. 14-3-3 sigma needs to form a homodimer to be functional, while dimers are less prone to degradation than mono...

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Bibliographic Details
Main Authors: Ghazi Aljabal (Author), Beow Keat Yap (Author)
Format: Book
Published: MDPI AG, 2022-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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