Drug-Like Small Molecule HSP27 Functional Inhibitor Sensitizes Lung Cancer Cells to Gefitinib or Cisplatin by Inducing Altered Cross-Linked Hsp27 Dimers

• 主要な著者: Hawon Yoo (著者), Seul-Ki Choi (著者), Jaeok Lee (著者), So Hyeon Park (著者), You Na Park (著者), Soo-Yeon Hwang (著者), Jae-Ho Shin (著者), Younghwa Na (著者), Youngjoo Kwon (著者), Hwa Jeong Lee (著者), Yun-Sil Lee (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2021-04-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Relationships between heat shock protein 27 (HSP27) and cancer aggressiveness, metastasis, drug resistance, and poor patient outcomes in various cancer types including non-small cell lung cancer (NSCLC) were reported, and inhibition of HSP27 expression is suggested to be a possible strategy for canc...