Drug-Like Small Molecule HSP27 Functional Inhibitor Sensitizes Lung Cancer Cells to Gefitinib or Cisplatin by Inducing Altered Cross-Linked Hsp27 Dimers

• Prif Awduron: Hawon Yoo (Awdur), Seul-Ki Choi (Awdur), Jaeok Lee (Awdur), So Hyeon Park (Awdur), You Na Park (Awdur), Soo-Yeon Hwang (Awdur), Jae-Ho Shin (Awdur), Younghwa Na (Awdur), Youngjoo Kwon (Awdur), Hwa Jeong Lee (Awdur), Yun-Sil Lee (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: MDPI AG, 2021-04-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Relationships between heat shock protein 27 (HSP27) and cancer aggressiveness, metastasis, drug resistance, and poor patient outcomes in various cancer types including non-small cell lung cancer (NSCLC) were reported, and inhibition of HSP27 expression is suggested to be a possible strategy for canc...