Identification of islet-enriched long non-coding RNAs contributing to β-cell failure in type 2 diabetes

• मुख्य लेखकों: Anna Motterle (लेखक), Sonia Gattesco (लेखक), Marie-Line Peyot (लेखक), Jonathan Lou S. Esguerra (लेखक), Ana Gomez-Ruiz (लेखक), D. Ross Laybutt (लेखक), Patrick Gilon (लेखक), Frédéric Burdet (लेखक), Mark Ibberson (लेखक), Lena Eliasson (लेखक), Marc Prentki (लेखक), Romano Regazzi (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2017-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Objective: Non-coding RNAs constitute a major fraction of the β-cell transcriptome. While the involvement of microRNAs is well established, the contribution of long non-coding RNAs (lncRNAs) in the regulation of β-cell functions and in diabetes development remains poorly understood. The aim of this...