Impact of the Gram-Negative-Selective Inhibitor MAC13243 on In Vitro Simulated Gut Microbiota

Impact of the Gram-Negative-Selective Inhibitor MAC13243 on In Vitro Simulated Gut Microbiota

New Gram-negative-selective antimicrobials are desirable to avoid perturbations in the gut microbiota leading to antibiotic-induced dysbiosis. We investigated the impact of a prototype drug (MAC13243) interfering with the Gram-negative outer membrane protein LolA on the faecal microbiota. Faecal sus...

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Bibliographic Details
Main Authors: Frida Svanberg Frisinger (Author), Mattia Pirolo (Author), Duncan Y. K. Ng (Author), Xiaotian Mao (Author), Dennis Sandris Nielsen (Author), Luca Guardabassi (Author)
Format: Book
Published: MDPI AG, 2022-06-01T00:00:00Z.
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