SOX2-Upregulated microRNA-30e Promotes the Progression of Esophageal Cancer via Regulation of the USP4/SMAD4/CK2 Axis

• Auteurs principaux: Yang Yang (Auteur), Xin Fan (Auteur), Yukai Ren (Auteur), Kai Wu (Auteur), Xiangyu Tian (Auteur), Fengbiao Wen (Auteur), Donglei Liu (Auteur), Yuxia Fan (Auteur), Song Zhao (Auteur)
• Format: Livre
• Publié: Elsevier, 2021-03-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Esophageal cancer (EC) is a highly aggressive disease, and its progression involves a complex gene regulation network. Transcription factor SOX2 is amplified in various cancers including EC. A pathway involving SOX2 regulation of microRNAs (miRNAs) and their target genes has been previously revealed...