SOX2-Upregulated microRNA-30e Promotes the Progression of Esophageal Cancer via Regulation of the USP4/SMAD4/CK2 Axis

• Main Authors: Yang Yang (Author), Xin Fan (Author), Yukai Ren (Author), Kai Wu (Author), Xiangyu Tian (Author), Fengbiao Wen (Author), Donglei Liu (Author), Yuxia Fan (Author), Song Zhao (Author)
• Format: Book
• Published: Elsevier, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Esophageal cancer (EC) is a highly aggressive disease, and its progression involves a complex gene regulation network. Transcription factor SOX2 is amplified in various cancers including EC. A pathway involving SOX2 regulation of microRNAs (miRNAs) and their target genes has been previously revealed...