Histomorphometric analysis of liver biopsies of treated patients with Gaucher disease type 1

• Egile Nagusiak: Rodrigo Tzovenos Starosta (Egilea), Marina Siebert (Egilea), Filippo Pinto e Vairo (Egilea), Bruno Lafaiete de Lima Costa (Egilea), Christiano Tomaso Ponzoni (Egilea), Ida Vanessa Doederlein Schwartz (Egilea), Carlos Thadeu Schmidt Cerski (Egilea)
• Formatua: Liburua
• Argitaratua: University of São Paulo, 2021-08-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Gaucher disease (GD) is an autosomal recessive lysosomal disorder caused by a disturbance in the metabolism of glucocerebroside in the macrophages. Most of its manifestations - hepatosplenomegaly, anemia, thrombocytopenia, and bone pain - are amenable to a macrophage-target therapy such as enzyme re...