Histomorphometric analysis of liver biopsies of treated patients with Gaucher disease type 1

• Main Authors: Rodrigo Tzovenos Starosta (Author), Marina Siebert (Author), Filippo Pinto e Vairo (Author), Bruno Lafaiete de Lima Costa (Author), Christiano Tomaso Ponzoni (Author), Ida Vanessa Doederlein Schwartz (Author), Carlos Thadeu Schmidt Cerski (Author)
• Format: Book
• Published: University of São Paulo, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Gaucher disease (GD) is an autosomal recessive lysosomal disorder caused by a disturbance in the metabolism of glucocerebroside in the macrophages. Most of its manifestations - hepatosplenomegaly, anemia, thrombocytopenia, and bone pain - are amenable to a macrophage-target therapy such as enzyme re...