Histomorphometric analysis of liver biopsies of treated patients with Gaucher disease type 1

• Glavni autori: Rodrigo Tzovenos Starosta (Autor), Marina Siebert (Autor), Filippo Pinto e Vairo (Autor), Bruno Lafaiete de Lima Costa (Autor), Christiano Tomaso Ponzoni (Autor), Ida Vanessa Doederlein Schwartz (Autor), Carlos Thadeu Schmidt Cerski (Autor)
• Format: Knjiga
• Izdano: University of São Paulo, 2021-08-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Gaucher disease (GD) is an autosomal recessive lysosomal disorder caused by a disturbance in the metabolism of glucocerebroside in the macrophages. Most of its manifestations - hepatosplenomegaly, anemia, thrombocytopenia, and bone pain - are amenable to a macrophage-target therapy such as enzyme re...