Antituberculosis Drugs (Rifampicin and Isoniazid) Induce Liver Injury by Regulating NLRP3 Inflammasomes

• 主要な著者: Qiang Su (著者), Wei Kuang (著者), Weiyi Hao (著者), Jing Liang (著者), Liang Wu (著者), Chunmei Tang (著者), Yali Wang (著者), Tao Liu (著者)
• フォーマット: 図書
• 出版事項: Hindawi Limited, 2021-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Patients being treated for pulmonary tuberculosis often suffer liver injury due to the effects of anti-TB drugs, and the underlying mechanisms for those injuries need to be clarified. In this study, rats and hepatic cells were administrated isoniazid (INH) and rifampin (RIF) and then treated with NL...