Antituberculosis Drugs (Rifampicin and Isoniazid) Induce Liver Injury by Regulating NLRP3 Inflammasomes

• Egile Nagusiak: Qiang Su (Egilea), Wei Kuang (Egilea), Weiyi Hao (Egilea), Jing Liang (Egilea), Liang Wu (Egilea), Chunmei Tang (Egilea), Yali Wang (Egilea), Tao Liu (Egilea)
• Formatua: Liburua
• Argitaratua: Hindawi Limited, 2021-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Patients being treated for pulmonary tuberculosis often suffer liver injury due to the effects of anti-TB drugs, and the underlying mechanisms for those injuries need to be clarified. In this study, rats and hepatic cells were administrated isoniazid (INH) and rifampin (RIF) and then treated with NL...